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Nasopharynx cancer

Nasopharynx cancer or nasopharyngeal carcinoma (NPC) is the most common cancer originating in the nasopharynx, most commonly in the postero-lateral nasopharynx or pharyngeal recess or 'Fossa of Rosenmüller' accounting for 50% cases. NPC occurs in children and adults. NPC differs significantly from other cancers of the head and neck in its occurrence, causes, clinical behavior, and treatment. It is vastly more common in certain regions of East Asia and Africa than elsewhere, with viral, dietary and genetic factors implicated in its causation. It is most common in males. It is a squamous cell carcinoma of an undifferentiated type. Squamous epithelial cells are a flat type of cell found in the skin and the membranes that line some body cavities.

What causes nasopharyngeal cancer?

 

The exact cause of nasopharyngeal cancer is unknown, but a number of factors can increase your risk of developing the condition.

These include:

  • being of south Chinese or north African descent
  • having a diet very high in salt-cured meats and fish
  • being exposed to the Epstein-Barr virus (EBV), a common virus that causes glandular fever
  • having a job where you're regularly exposed to hardwood dust
  • having a first-degree relative, such as a parent, who's had the condition

Symptoms of nasopharyngeal cancer

It's often difficult to recognise nasopharyngeal cancer because the symptoms are similar to other, less serious conditions.

Also, many people with nasopharyngeal cancer don't have any symptoms until the cancer reaches an advanced stage.

Symptoms of nasopharyngeal cancer can include:

  • a lump in the neck
  • hearing loss (usually only in 1 ear)
  • tinnitus (hearing sounds that come from inside the body rather than from an outside source)
  • a blocked or stuffy nose
  • nosebleeds
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